Heterozygote of TAP1 Codon637 decreases susceptibility to HPV infection but increases susceptibility to esophageal cancer among the Kazakh populations

Table 1 Analysis of the association between HPV infection and Kazakh patients with esophageal carcinoma

Types	Case (n = 361)	Control (n = 66)	χ ²	OR (95 % CI)
Types	n (%)^a	n (%)^a	χ ²	OR (95 % CI)
HPV L1	204 (64.6)	12 (18.2)	47.786***	8.196 (4.28–15.964)
HPV16E7	130(41.1)	10 (15.2)	15.881***	3.941 (1.926–7.955)
HPV18E7	80 (25.3)	6 (9.1)	8.240**	3.390 (1.411–8.145)
HPV31E7	45(14.2)	3 (4.5)	4.671*	3.487 (1.050–11.582)
HPV45E7	23(7.3)	1 (1.5)	3.080	5.102 (0.677–38.466)
Multiple infection	56(17.7)	3 (4.5)	7.258**	4.523 (1.371–14.922)

“*”represents P < 0.05, “**”indicates P < 0.01, “***”depicts P < 0.001
^aBecause of the multiple infection, the total HPV-positive rate was smaller than the sum of the positive rates of each subtype

ISSN: 1756-9966