Fig. 6

Anti-miR-93 and PTEN vector suppressed in vivo tumor growth. Four groups were; (1) untreated (n = 7); (2) transfected with of negative control-miRs (n = 7); (3) transfected with anti-miR-93 (n = 7); and (4) transfected with PTEN expression vector (n = 7). Tumor volumes were measured at the time points indicated after the tumor cell inoculation. (**) P < 0.01. Immunofluorescence of PTEN (c) and p-Akt (f) following transfection of anti-miR-93 and PTEN vector into tumor cells. The number of PTEN (d) and p-Akt (f) positive cells per unit area in the tumor lesion