Fig. 3

TMEM158 knockdown impaired cell proliferation and cell cycle in HO-8910 (a and c) and A2780 cells (b and d). Results of CCK-8 assay performed in control cells and TMEM158 knockdown cells were shown in (a and b). The percentage of cells in G1, S and G2-M phase for each sample at 48 h after viral infection were shown in (c and d). Data were based on at least 3 independent experiments, and shown as mean ± SEM. WT: wild type cells; NC: scrambled shRNA virus infected cells; TMEM158-Ri-1: TMEM158-shRNA-1 virus infected cells. Data were shown as the mean value ± SEM. **P < 0.01, as compared with NC cells