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Table 3 The diagnosis value between early stage of CRC and normal controls

From: Plasma levels of microRNA-24, microRNA-320a, and microRNA-423-5p are potential biomarkers for colorectal carcinoma

Variables

miR-24

miR-320a

miR-423-5p

CEA

CA19-9

Cut-off

−1.731

−1.006

−0.854

5 ng/ml

27U/ml

Sensitivity

77.78 %

90.74 %

88.89 %

20.37 %

20.37 %

Specificity

83.85 %

73.08 %

70.77 %

95.38 %

93.08 %

PPV

66.67 %

58.33 %

55.81 %

64.71 %

55 %

NPV

90.08 %

95 %

82.88 %

74.25 %

73.78 %

Diagnosis efficiency

82.07 %

78.26 %

76.09 %

73.37 %

71.74 %