Table 4 nDDIs described between general and OTC medications
From: A pilot study on the impact of known drug-drug interactions in cancer patients
Interaction | N. of cases | Description | Severity |
|---|---|---|---|
Warfarin x corticosteroids | 1 | Increased or decreased in anticoagulant effect of warfarin, unknown mechanism | Moderate |
Proton pump inhibitors x phenytoin | 2 | Increased dosage of anticonvulsant required | Minor |
Ondansetron x Opioids | 1 | Severe constipation | Moderate |
Acetylsalicylic acid x Warfarin | 4 | Increased anticoagulant effect of warfarin | Major |
Acetylsalicylic acid x ACE inhibitors/beta-blockers | 2 | Lowering blood pressure effect of ACE inhibitors and beta-blockers may be reduced by prostaglandin synthesis inhibition | Minor |