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Table 2 Univariate and multivariate analyses of prognostic parameters for survival in patients with pancreatic ductal adenocarcinoma (PDAC)

From: High expression of DDR1 is associated with the poor prognosis in Chinese patients with pancreatic ductal adenocarcinoma

  Univariate analysis Multivariate analysis
Prognostic parameter RR 95 % CI P value RR 95 % CI P value
DDR1 (low vs.high) 0.613 0.439–0.857 0.004a 0.643 0.457–0.904 0.011a
Age (<65 vs. ≥65) 1.460 1.066–2.000 0.019a 1.533 1.107–2.122 0.010a
Gender (male vs. female) 0.765 0.552–1.058 0.105    
Tumor location (head vs. body/tail) 0.999 0.713–1.399 0.996    
Size (≤2 cm vs. >2 cm) 1.641 0.978–2.754 0.061    
Tumor differentiation (well vs. moderate/poor) 2.125 0.938–4.813 0.071    
T classification (T1 vs. T2 vs. T3 vs. T4) 1.104 0.871–1.400 0.412    
AJCC stage (I vs. II vs. III vs. IV) 1.260 0.992–1.600 0.059    
N classification (absent vs. present) 1.811 1.290–2.541 0.001a 1.769 1.242–2.519 0.002a
Liver metastasis (absent vs. present) 3.299 1.746–6.235 0.000a 2.748 1.419–5.320 0.003a
Vascular invasion (absent vs. present) 1.492 0.955–2.334 0.079    
  1. HR hazard ratio, CI confidence interval
  2. AJCC staging is according to the 7th edition of the American Joint Committee on Cancer (AJCC) staging system [29]
  3. aStatistical significant (P < 0.05)