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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Mutation status concordance between primary lesions and metastatic sites of advanced non-small-cell lung cancer and the impact of mutation testing methodologies: a literature review

Fig. 2

EGFR mutation pattern in 56 primary tumour and 30 lymph node metastasis sites obtained from nine patients with EGFR-mutant lung adenocarcinomas. A homogeneous mutation pattern was detected in five primary tumours (cases 2, 3, 4, 7 and 9) and all but one (case 6) metastasis case. Case 6 had mixed wild-type and mutant sites in both primary tumour sites and corresponding metastases. EGFR, epidermal growth factor receptor. Reprinted from Cancer Prev Res (Phila), 2008, 1, 192–200, Tang et al., Epidermal growth factor receptor abnormalities in the pathogenesis and progression of lung adenocarcinomas, with permission from AACR [60]

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