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Table 1 Expression of ANXA2 and HE4 in different endometrial tissues

From: Expression and clinical significance of annexin A2 and human epididymis protein 4 in endometrial carcinoma

Groups Cases ANXA2 HE4
- + ++ +++ Positive (%) - + ++ +++ Positive (%)
Malignant 84 4 25 27 28 95.2 %a 12 34 25 13 85.7 %c,d
Atypical 30 5 9 7 9 83.3 %b 10 13 7 0 66.7 %e
Severe 13 2 3 3 5 84.6 % 3 5 5 0 76.9 %
Moderate 9 1 3 3 2 88.9 % 2 5 2 0 77.8 %
Mild 8 2 3 1 2 75.0 % 5 3 0 0 37.5 %
Normal 18 8 2 1 7 55.6 % 15 3 0 0 16.7 %
Proliferative 9 5 1 0 3 44.4 % 8 1 0 0 11.1 %
Secretory 9 3 1 1 4 66.7 % 7 2 0 0 22.2 %
  1. a,bpositive ANXA2 cases in malignant and atypical, respectively, compared with normal group, both p < 0.05 (p a < 0.001, p b = 0.049)
  2. c,dpositive HE4 cases in malignant compared with atypical and normal group, respectively, both p < 0.05 (p c = 0.023, p d < 0.001)
  3. epositive HE4 cases in atypical group campared with normal group, p < 0.05 (p e = 0.001)