Expression and clinical significance of annexin A2 and human epididymis protein 4 in endometrial carcinoma

Table 1 Expression of ANXA2 and HE4 in different endometrial tissues

Groups	Cases	ANXA2					HE4
Groups	Cases	-	+	++	+++	Positive (%)	-	+	++	+++	Positive (%)
Malignant	84	4	25	27	28	95.2 %^a	12	34	25	13	85.7 %^c,d
Atypical	30	5	9	7	9	83.3 %^b	10	13	7	0	66.7 %^e
Severe	13	2	3	3	5	84.6 %	3	5	5	0	76.9 %
Moderate	9	1	3	3	2	88.9 %	2	5	2	0	77.8 %
Mild	8	2	3	1	2	75.0 %	5	3	0	0	37.5 %
Normal	18	8	2	1	7	55.6 %	15	3	0	0	16.7 %
Proliferative	9	5	1	0	3	44.4 %	8	1	0	0	11.1 %
Secretory	9	3	1	1	4	66.7 %	7	2	0	0	22.2 %

^a,bpositive ANXA2 cases in malignant and atypical, respectively, compared with normal group, both p < 0.05 (p _a < 0.001, p _b = 0.049)
^c,dpositive HE4 cases in malignant compared with atypical and normal group, respectively, both p < 0.05 (p _c = 0.023, p _d < 0.001)
^epositive HE4 cases in atypical group campared with normal group, p < 0.05 (p _e = 0.001)

ISSN: 1756-9966