Fig. 3
DDR regulates HCC cell mobility and EMT phenotype. a Cell migration and invasion as measured by Transwell assays were promoted by up-regulation of DDR2 in Hep3B cells as compared with control cells (n = 6, P < 0.01). b Cell migration and invasion as measured by Transwell assays were inhibited by down-regulation of DDR2 in MHCC-97H cells as compared with control cells (n = 6, P < 0.01). c Immunoblotting analysis of E-cadherin and Vimentin in Hep3B cells with DDR2 expressing plasmid transfection or control plasmid transfection (n = 6, P < 0.01). d Immunoblotting analysis of E-cadherin and Vimentin in MHCC-97H cells with DDR2-shRNA transfection or control-shRNA transfection (n = 6, P < 0.01)