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Table 4 Multivariate analysis of factors contributing to overall survival and disease-free survival in HCC patients

From: DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1

Variable Overall survival rate Disease-free survival rate
HR (95 % CI)a P value HR (95 % CI)a P value
HBsAg statusb 3.021(1.335–6.836) 0.008* 2.556 (1.300–5.026) 0.007*
Tumor number 2.374 (1.117–5.045) 0.025* 2.758 (1.363–5.579) 0.005*
Vascular invasion 0.912 (0.451–1.847) 0.799 1.086 (0.553–2.136) 0.810
TNM stage 1.269 (0.579–2.784) 0.552 0.950 (0.463–1.953) 0.890
Edmondson grade 0.999 (0.574–1.739) 0.998 1.389 (0.854–2.260) 0.185
DDR2 level 2.169 (1.198–3.927) 0.011* 2.051 (1.228–3.425) 0.006*
  1. a HR hazard ratio, b HbsAg hepatitis B surface antigen, CI confidence interval, *P < 0.05