TY - JOUR AU - Thomas, M. B. AU - Jaffe, D. AU - Choti, M. M. AU - Belghiti, J. AU - Curley, S. AU - Fong, Y. PY - 2010 DA - 2010// TI - Hepatocellular carcinoma: consensus recommendations of the National Cancer Institute Clinical Trials Planning Meeting JO - J Clin Oncol VL - 28 UR - https://doi.org/10.1200/JCO.2010.28.7805 DO - 10.1200/JCO.2010.28.7805 ID - Thomas2010 ER - TY - JOUR AU - Siegel, R. L. AU - Miller, K. D. AU - Jemal, A. PY - 2015 DA - 2015// TI - Cancer statistics, 2015 JO - CA Cancer J Clin VL - 65 UR - https://doi.org/10.3322/caac.21254 DO - 10.3322/caac.21254 ID - Siegel2015 ER - TY - JOUR AU - El-Serag, H. B. AU - Kanwal, F. PY - 2014 DA - 2014// TI - Epidemiology of hepatocellular carcinoma in the United States: where are we? Where do we go? JO - Hepatology VL - 60 UR - https://doi.org/10.1002/hep.27222 DO - 10.1002/hep.27222 ID - El-Serag2014 ER - TY - JOUR AU - Deng, L. AU - Yang, S. B. AU - Xu, F. F. AU - Zhang, J. H. PY - 2015 DA - 2015// TI - Long noncoding RNA CCAT1 promotes hepatocellular carcinoma progression by functioning as let-7 sponge JO - J Exp Clin Cancer Res. VL - 34 UR - https://doi.org/10.1186/s13046-015-0136-7 DO - 10.1186/s13046-015-0136-7 ID - Deng2015 ER - TY - JOUR AU - Du, C. AU - Weng, X. AU - Hu, W. AU - Lv, Z. AU - Xiao, H. AU - Ding, C. PY - 2015 DA - 2015// TI - Hypoxia-inducible MiR-182 promotes angiogenesis by targeting RASA1 in hepatocellular carcinoma JO - J Exp Clin Cancer Res. VL - 34 UR - https://doi.org/10.1186/s13046-015-0182-1 DO - 10.1186/s13046-015-0182-1 ID - Du2015 ER - TY - JOUR AU - Stauffer, J. K. AU - Scarzello, A. J. AU - Jiang, Q. AU - Wiltrout, R. H. PY - 2012 DA - 2012// TI - Chronic inflammation, immune escape, and oncogenesis in the liver: a unique neighborhood for novel intersections JO - Hepatology VL - 56 UR - https://doi.org/10.1002/hep.25674 DO - 10.1002/hep.25674 ID - Stauffer2012 ER - TY - JOUR AU - Trépo, C. AU - Chan, H. L. AU - Lok, A. PY - 2014 DA - 2014// TI - Hepatitis B virus infection JO - Lancet VL - 384 UR - https://doi.org/10.1016/S0140-6736(14)60220-8 DO - 10.1016/S0140-6736(14)60220-8 ID - Trépo2014 ER - TY - STD TI - de Martel C, Maucort-Boulch D, Plummer M, Franceschi S. Worldwide relative contribution of hepatitis B and C viruses in hepatocellular carcinoma. Hepatology. 2015; 3. doi: 10.1002/hep.27969. [Epub ahead of print] ID - ref8 ER - TY - JOUR AU - Chang, T. S. AU - Wu, Y. C. AU - Chi, C. C. AU - Su, W. C. AU - Chang, P. J. AU - Lee, K. F. PY - 2015 DA - 2015// TI - Activation of IL6/IGFIR confers poor prognosis of HBV-related hepatocellular carcinoma through induction of OCT4/NANOG expression JO - Clin Cancer Res VL - 21 UR - https://doi.org/10.1158/1078-0432.CCR-13-3274 DO - 10.1158/1078-0432.CCR-13-3274 ID - Chang2015 ER - TY - JOUR AU - Lin, L. AU - Han, M. M. AU - Wang, F. AU - Xu, L. L. AU - Yu, H. X. AU - Yang, P. Y. PY - 2014 DA - 2014// TI - CXCR7 stimulates MAPK signaling to regulate hepatocellular carcinoma progression JO - Cell Death Dis. VL - 5 UR - https://doi.org/10.1038/cddis.2014.392 DO - 10.1038/cddis.2014.392 ID - Lin2014 ER - TY - JOUR AU - Yuan, J. H. AU - Yang, F. AU - Wang, F. AU - Ma, J. Z. AU - Guo, Y. J. AU - Tao, Q. F. PY - 2014 DA - 2014// TI - A long noncoding RNA activated by TGF-β promotes the invasion-metastasis cascade in hepatocellular carcinoma JO - Cancer Cell VL - 25 UR - https://doi.org/10.1016/j.ccr.2014.03.010 DO - 10.1016/j.ccr.2014.03.010 ID - Yuan2014 ER - TY - JOUR AU - Wan, S. AU - Zhao, E. AU - Kryczek, I. AU - Vatan, L. AU - Sadovskaya, A. AU - Ludema, G. PY - 2014 DA - 2014// TI - Tumor-associated macrophages produce interleukin 6 and signal via STAT3 to promote expansion of human hepatocellular carcinoma stem cells JO - Gastroenterology VL - 147 UR - https://doi.org/10.1053/j.gastro.2014.08.039 DO - 10.1053/j.gastro.2014.08.039 ID - Wan2014 ER - TY - JOUR AU - Sheng, T. AU - Wang, B. AU - Wang, S. Y. AU - Deng, B. AU - Qu, L. AU - Qi, X. S. PY - 2015 DA - 2015// TI - The relationship between serum interleukin-6 and the recurrence of hepatitis B virus related hepatocellular carcinoma after curative resection JO - Medicine (Baltimore) VL - 94 UR - https://doi.org/10.1097/MD.0000000000000941 DO - 10.1097/MD.0000000000000941 ID - Sheng2015 ER - TY - JOUR AU - Kao, J. T. AU - Feng, C. L. AU - Yu, C. J. AU - Tsai, S. M. AU - Hsu, P. N. AU - Chen, Y. L. PY - 2015 DA - 2015// TI - IL-6, through p-STAT3 rather than p-STAT1, activates hepatocarcinogenesis and affects survival of hepatocellular carcinoma patients: a cohort study JO - BMC Gastroenterol. VL - 15 UR - https://doi.org/10.1186/s12876-015-0283-5 DO - 10.1186/s12876-015-0283-5 ID - Kao2015 ER - TY - JOUR AU - Martin, L. AU - Chang, H. Y. PY - 2012 DA - 2012// TI - Uncovering the role of genomic “dark matter” in human disease JO - J Clin Invest VL - 122 UR - https://doi.org/10.1172/JCI60020 DO - 10.1172/JCI60020 ID - Martin2012 ER - TY - JOUR AU - Wang, Y. AU - He, L. AU - Du, Y. AU - Zhu, P. AU - Huang, G. AU - Luo, J. PY - 2015 DA - 2015// TI - The long noncoding RNA lncTCF7 promotes self-renewal of human liver cancer stem cells through activation of Wnt signaling JO - Cell Stem Cell VL - 16 UR - https://doi.org/10.1016/j.stem.2015.03.003 DO - 10.1016/j.stem.2015.03.003 ID - Wang2015 ER - TY - JOUR AU - Han, X. AU - Yang, F. AU - Cao, H. AU - Liang, Z. PY - 2015 DA - 2015// TI - Malat1 regulates serum response factor through miR-133 as a competing endogenous RNA in myogenesis JO - FASEB J VL - 29 UR - https://doi.org/10.1096/fj.14-259952 DO - 10.1096/fj.14-259952 ID - Han2015 ER - TY - JOUR AU - Li, P. AU - Ruan, X. AU - Yang, L. AU - Kiesewetter, K. AU - Zhao, Y. AU - Luo, H. PY - 2015 DA - 2015// TI - A liver-enriched long non-coding RNA, lncLSTR, regulates systemic lipid metabolism in mice JO - Cell Metab VL - 21 UR - https://doi.org/10.1016/j.cmet.2015.02.004 DO - 10.1016/j.cmet.2015.02.004 ID - Li2015 ER - TY - JOUR AU - Han, P. AU - Li, W. AU - Lin, C. H. AU - Yang, J. AU - Shang, C. AU - Nurnberg, S. T. PY - 2014 DA - 2014// TI - A long noncoding RNA protects the heart from pathological hypertrophy JO - Nature VL - 514 UR - https://doi.org/10.1038/nature13596 DO - 10.1038/nature13596 ID - Han2014 ER - TY - JOUR AU - Tang, J. AU - Zhuo, H. AU - Zhang, X. AU - Jiang, R. AU - Ji, J. AU - Deng, L. PY - 2014 DA - 2014// TI - A novel biomarker Linc00974 interacting with KRT19 promotes proliferation and metastasis in hepatocellular carcinoma JO - Cell Death Dis. VL - 5 UR - https://doi.org/10.1038/cddis.2014.518 DO - 10.1038/cddis.2014.518 ID - Tang2014 ER - TY - STD TI - Fu WM, Zhu X, Wang WM, Lu YF, Hu BG, Wang H, et al. Hotair Mediates Hepatocarcinogenesis through Suppressing MiRNA-218 Expression and Activating P14 and P16 Signaling. J Hepatol. 2015; 26. S0168-8278(15)00343-8. doi: 10.1016/j.jhep.2015.05.016. [Epub ahead of print] ID - ref21 ER - TY - JOUR AU - Zhang, L. AU - Yang, F. AU - Yuan, J. H. AU - Yuan, S. X. AU - Zhou, W. P. AU - Huo, X. S. PY - 2013 DA - 2013// TI - Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma JO - Carcinogenesis VL - 34 UR - https://doi.org/10.1093/carcin/bgs381 DO - 10.1093/carcin/bgs381 ID - Zhang2013 ER - TY - STD TI - Yuan SX, Wang J, Yang F, Tao QF, Zhang J, Wang LL, et al. Long noncoding RNA DANCR increases stemness features of hepatocellular carcinoma via de-repression of CTNNB1. Hepatology. 2015; doi: 10.1002/hep.27893. [Epub ahead of print] ID - ref23 ER - TY - JOUR AU - Huang, J. F. AU - Guo, Y. J. AU - Zhao, C. X. AU - Yuan, S. X. AU - Wang, Y. AU - Tang, G. N. PY - 2013 DA - 2013// TI - Hepatitis B virus X protein (HBx)-related long noncoding RNA (lncRNA) down-regulated expression by HBx (Dreh) inhibits hepatocellular carcinoma metastasis by targeting the intermediate filament protein vimentin JO - Hepatology VL - 57 UR - https://doi.org/10.1002/hep.26195 DO - 10.1002/hep.26195 ID - Huang2013 ER - TY - JOUR AU - Yuan, S. X. AU - Yang, F. AU - Yang, Y. AU - Tao, Q. F. AU - Zhang, J. AU - Huang, G. PY - 2012 DA - 2012// TI - Long noncoding RNA associated with microvascular invasion in hepatocellular carcinoma promotes angiogenesis and serves as a predictor for hepatocellular carcinoma patients’ poor recurrence-free survival after hepatectomy JO - Hepatology VL - 56 UR - https://doi.org/10.1002/hep.25895 DO - 10.1002/hep.25895 ID - Yuan2012 ER - TY - JOUR AU - Yang, F. AU - Zhang, L. AU - Huo, X. S. AU - Yuan, J. H. AU - Xu, D. AU - Yuan, S. X. PY - 2011 DA - 2011// TI - Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans JO - Hepatology VL - 54 UR - https://doi.org/10.1002/hep.24563 DO - 10.1002/hep.24563 ID - Yang2011 ER - TY - JOUR AU - Hämmerle, M. AU - Gutschner, T. AU - Uckelmann, H. AU - Ozgur, S. AU - Fiskin, E. AU - Gross, M. PY - 2013 DA - 2013// TI - Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1) JO - Hepatology VL - 58 UR - https://doi.org/10.1002/hep.26537 DO - 10.1002/hep.26537 ID - Hämmerle2013 ER - TY - JOUR AU - Yang, F. AU - Huo, X. S. AU - Yuan, S. X. AU - Zhang, L. AU - Zhou, W. P. AU - Wang, F. PY - 2013 DA - 2013// TI - Repression of the long noncoding RNA-LET by histone deacetylase 3 contributes to hypoxia-mediated metastasis JO - Mol Cell VL - 49 UR - https://doi.org/10.1016/j.molcel.2013.01.010 DO - 10.1016/j.molcel.2013.01.010 ID - Yang2013 ER - TY - JOUR AU - Wang, F. AU - Yuan, J. H. AU - Wang, S. B. AU - Yang, F. AU - Yuan, S. X. AU - Ye, C. PY - 2014 DA - 2014// TI - Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2 JO - Hepatology VL - 60 UR - https://doi.org/10.1002/hep.27239 DO - 10.1002/hep.27239 ID - Wang2014 ER - TY - JOUR AU - Tam, W. L. AU - Weinberg, R. A. PY - 2013 DA - 2013// TI - The epigenetics of epithelial-mesenchymal plasticity in cancer JO - Nat Med VL - 19 UR - https://doi.org/10.1038/nm.3336 DO - 10.1038/nm.3336 ID - Tam2013 ER - TY - JOUR AU - Nieto, M. A. PY - 2013 DA - 2013// TI - Epithelial plasticity: a common theme in embryonic and cancer cells JO - Science VL - 342 UR - https://doi.org/10.1126/science.1234850 DO - 10.1126/science.1234850 ID - Nieto2013 ER - TY - JOUR AU - Rhim, A. D. PY - 2013 DA - 2013// TI - Epithelial to mesenchymal transition and the generation of stem-like cells in pancreatic cancer JO - Pancreatology VL - 13 UR - https://doi.org/10.1016/j.pan.2013.01.004 DO - 10.1016/j.pan.2013.01.004 ID - Rhim2013 ER - TY - JOUR AU - Liu, H. AU - Ren, G. AU - Wang, T. AU - Chen, Y. AU - Gong, C. AU - Bai, Y. PY - 2015 DA - 2015// TI - Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial-mesenchymal transition JO - Carcinogenesis VL - 36 UR - https://doi.org/10.1093/carcin/bgv017 DO - 10.1093/carcin/bgv017 ID - Liu2015 ER - TY - STD TI - Crusz SM, Balkwill FR. Inflammation and cancer: advances and new agents. Nat Rev Clin Oncol. 2015; doi:10.1038/nrclinonc.2015.105. [Epub ahead of print] ID - ref34 ER - TY - JOUR AU - Lin, L. AU - Liu, A. AU - Peng, Z. AU - Lin, H. J. AU - Li, P. K. AU - Li, C. AU - Lin, J. PY - 2011 DA - 2011// TI - STAT3 is necessary for proliferation and survival in colon cancer-initiating cells JO - Cancer Res VL - 71 UR - https://doi.org/10.1158/0008-5472.CAN-10-4660 DO - 10.1158/0008-5472.CAN-10-4660 ID - Lin2011 ER - TY - JOUR AU - Marotta, L. L. AU - Almendro, V. AU - Marusyk, A. AU - Shipitsin, M. AU - Schemme, J. AU - Walker, S. R. PY - 2011 DA - 2011// TI - The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24− stem cell-like breast cancer cells in human tumors JO - J Clin Invest VL - 121 UR - https://doi.org/10.1172/JCI44745 DO - 10.1172/JCI44745 ID - Marotta2011 ER - TY - STD TI - Buchert M, Burns CJ, Ernst M. Targeting JAK kinase in solid tumors: emerging opportunities and challenges. Oncogene. 2015 May 18. doi:10.1038/onc.2015.150. [Epub ahead of print] ID - ref37 ER - TY - JOUR AU - Liu, Y. AU - Luo, F. AU - Xu, Y. AU - Wang, B. AU - Zhao, Y. AU - Xu, W. PY - 2015 DA - 2015// TI - Epithelial-mesenchymal transition and cancer stem cells, mediated by a long non-coding RNA, HOTAIR, are involved in cell malignant transformation induced by cigarette smoke extract JO - Toxicol Appl Pharmacol VL - 282 UR - https://doi.org/10.1016/j.taap.2014.10.022 DO - 10.1016/j.taap.2014.10.022 ID - Liu2015 ER - TY - STD TI - Li Y, Shi Y, McCaw L, Li YJ, Zhu F, Gorczynski R, et al. Microenvironmental interleukin-6 suppresses toll-like receptor signaling in human leukemia cells through miR-17/19A. Blood. 2015 Jun 3. pii: blood-2014-12-618678. [Epub ahead of print] ID - ref39 ER - TY - JOUR AU - Li, C. H. AU - Xu, F. AU - Chow, S. AU - Feng, L. AU - Yin, D. AU - Ng, T. B. PY - 2014 DA - 2014// TI - Hepatitis B virus X protein promotes hepatocellular carcinoma transformation through interleukin-6 activation of microRNA-21 expression JO - Eur J Cancer VL - 50 UR - https://doi.org/10.1016/j.ejca.2014.07.008 DO - 10.1016/j.ejca.2014.07.008 ID - Li2014 ER - TY - JOUR AU - Rokavec, M. AU - Öner, M. G. AU - Li, H. AU - Jackstadt, R. AU - Jiang, L. AU - Lodygin, D. PY - 2014 DA - 2014// TI - IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis JO - J Clin Invest VL - 124 UR - https://doi.org/10.1172/JCI73531 DO - 10.1172/JCI73531 ID - Rokavec2014 ER -