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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: Long noncoding RNA lncTCF7, induced by IL-6/STAT3 transactivation, promotes hepatocellular carcinoma aggressiveness through epithelial-mesenchymal transition

Fig. 5

lncTCF7 plays a critical role in IL-6 induced EMT. a qRT-PCR analysis of lncTCF7 expression following treatment of SK-Hep-1 cells with two individual siRNAs targeting lncTCF7. b Morphology of SK-Hep-1 cells with siRNAs against lncTCF7 or scrambled control and stimulated with 50 ng/mL of IL-6 for 72 h. qRT-PCR analysis (c) and western blots (d) of 72 h IL-6 treated SK-Hep-1 cells receiving the indicated siRNAs of EMT specific marker E-cadherin and Vimentin. Data represent the mean ± S.D. from three independent experiments.*p < 0.05.*p < 0.05

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