Fig. 2

The changes of the cell morphologies and cell nuclei caused by increasing concentrations of oleandrin. (a/b) The morphology of U2OS (a) and SaOS-2 (b) cells was observed with an optical microscope at 50×, 100× and 200× magnification. c Nuclei staining of U2OS and SaOS-2 cells was performed with DAPI and was photographed at 400× magnification (karyopyknosis: arrow pointing; karyorrhexis: arrowhead pointing)