Clinicopathological features | Â | NAV2 expression | Â | ||
---|---|---|---|---|---|
n | Low (n = 47) | High (n = 91) | P value | ||
Age (years) | <65 | 67 | 25 | 42 | 0.433 |
 | ≥65 | 71 | 22 | 49 |  |
Gender | Male | 80 | 30 | 50 | 0.316 |
 | Female | 58 | 17 | 41 |  |
Tumor location | Left colon | 45 | 16 | 29 | 0.408 |
 | Right colon | 45 | 12 | 33 |  |
 | Rectum | 48 | 19 | 29 |  |
Tumor differentiation | Well-Moderate | 72 | 24 | 48 | 0.851 |
 | Poor | 66 | 23 | 43 |  |
TNM stage | I-II | 37 | 27 | 10 | < 0.0001 |
 | III-IV | 101 | 20 | 81 |  |
Depth of invasion | T1-T2 | 43 | 27 | 16 | < 0.001 |
 | T3-T4 | 95 | 20 | 75 |  |
Lymph node metastasis | N0 | 39 | 23 | 16 | 0.0001 |
 | N1-N2 | 99 | 24 | 75 |  |
Distant metastasis | M0 | 119 | 45 | 74 | 0.020 |
 | M1 | 19 | 2 | 17 |  |
CEA | <5Â ng/ml | 85 | 31 | 54 | 0.449 |
 | ≥5 ng/ml | 53 | 16 | 37 |  |
Adjuvant therapy | YES | 94 | 35 | 59 | 0.250 |
 | NO | 44 | 12 | 32 |  |