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Table 1 Relationship between clinicopathological characteristics, t-rpS6, p-rpS6 expressions and survival time (Log-rank)

From: Hyperphosphorylation of ribosomal protein S6 predicts unfavorable clinical survival in non-small cell lung cancer

Factors

n (%)

Median survival time (months)

Log rank P

Gender

Male

244 (77.22)

28

0.083

Female

72 (22.78)

32

Age/years

<60

130 (41.14)

28

0.942

≥60

186 (58.86)

31

Histological type

ADC

142 (44.94)

23

0.146

SCC

132 (41.77)

32

Others

42 (13.29)

22

Histological differentiation

Poor

150 (47.47)

25

0.008*

Moderate/Well

166 (50.63)

32

Tumor size

T1 + T2

167 (52.85)

36

<0.001*

T3 + T4

149 (47.15)

21

Lymph node invasion

N0

138 (43.67)

37

<0.001*

N1 + N2 + N3

178 (56.33)

25

Distant metastasis

M0

294 (93.04)

31

0.005*

M1

22 (6.96)

17

Stage

I

87 (27.53)

56

<0.001*

II + III + IV

229 (72.47)

22

t-rpS6

P

262 (82.91)

28

0.230

N

54 (17.09)

35

p-rpS6

P

165 (52.22)

20

<0.001*

N

151 (47.78)

42

p-rpS6/t-rpS6

≥0.67

188 (59.49)

12

<0.001*

<0.67

128 (40.51)

48

  1. t-rpS6 total rpS6; p-rpS6 phosphorylation of rpS6; ADC adenocarcinoma; SCC squamous cell carcinoma; P positive expression; N negative expression
  2. *: P < 0.05