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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: The frequency of osteolytic bone metastasis is determined by conditions of the soil, not the number of seeds; evidence from in vivo models of breast and prostate cancer

Fig. 6

Differences of bone remodelling activities between young and mature female BALB/c nude mice. a & b BV/TV was compared between 6-week old (Young) or 16-week old (Mature) female mice using the micro-CT analysis. n > 6, scale bar = 500μm. c The bone formation marker (Osteocalcin) and d bone resorption marker (TRAP) were also measured in mouse serum sample by ELISA, n = 5. e The number of osteoblasts per mm endocortical bone surface (N. Ob/B.Pm), f bone surface covered by osteoblasts (Ob.Pm/B.Pm), g number of osteoclasts per mm endocortical bone surface (N.Oc/B.Pm), and h bone surface covered by osteoclasts (Oc.Pm/B.Pm) were all compared between young and mature mice. n > 4, * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, t-test

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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