Xenograft model | Treatment | Mean ± SE tumor weight (g) | Tumor growth inhibition (%)a | p value versus vehicle |
---|---|---|---|---|
GC09-0109 | Vehicle | 1.14 (0.12) | Â | Â |
Reg 5 | 0.21 (0.03) | 81.4 | <0.001 | |
Reg 10 | 0.17 (0.02) | 84.9 | <0.001 | |
Reg 15 | 0.14 (0.02) | 88.1 | <0.001 | |
GC28-1107 | Vehicle | 1.72 (0.16) | Â | Â |
Reg 5 | 0.48 (0.06) | 72.4 | <0.001 | |
Reg 10 | 0.39 (0.06) | 77.6 | <0.001 | |
Reg 15 | 0.21 (0.03) | 88.0 | <0.001 | |
GC09-0109 | Vehicle | 0.92 (0.05) | Â | Â |
Reg 10 | 0.14 (0.01) | 84.9 | <0.01 | |
GC22-0808 | Vehicle | 2.55 (0.27) | Â | Â |
Reg 10 | 0.11 (0.01) | 95.9 | <0.001 | |
GC17-0409 | Vehicle | 2.03 (0.22) | Â | Â |
Reg 10 | 0.36 (0.05) | 82.4 | <0.001 | |
GC10-0608 | Vehicle | 3.11 (0.35) | Â | Â |
Reg 10 | 0.31 (0.04) | 90.0 | <0.001 | |
GC28-1107 | Vehicle | 1.40 (0.12) | Â | Â |
Reg 10 | 0.40 (0.02) | 71.5 | <0.001 | |
GC23-0909 | Vehicle | 1.73 (0.11) | Â | Â |
Reg 10 | 0.22 (0.02) | 87.0 | <0.001 | |
GC30-0309 | Vehicle | 3.48 (0.28) | Â | Â |
Reg 10 | 0.59 (0.07) | 83.0 | <0.001 | |
GC05-0208B | Vehicle | 2.17 (0.10) | Â | Â |
Reg 10 | 0.49 (0.03) | 77.6 | <0.001 |