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Table 3 Mean and Median ASE values of cases and controls for APC c.1458C > T assay

From: Correlation between mutations and mRNA expression of APC and MUTYH genes: new insight into hereditary colorectal polyposis predisposition

Status N Mean (±SD) Median Min Max Shapiro-Wilk Multiple comparison of Kruskall-Wallis vs control
Controlsb 68 1.25 (0.21) 1.20 0.89 1.92 0.014  
APC + polyposis cases 7a 1.20 (0.41) 1.38 0.43 1.60 0.499 0.560
APC - polyposis cases 13 1.11 (0.18) 1.11 0.83 1.51 0.682 0.029
CRC casesb 52 1.30 (0.32) 1.28 0.68 2.46 0.041 0.350
Overall 140 1.26 (0.27) 1.22 0.43 2.46   
  1. aCase GD41 was not considered in the table because it showed monoallelic expression
  2. bPreviously published [11]
  3. Bold values indicate statistical significance