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Table 4 Distribution of cases and controls at 1.0 SD from the overall mean ASE for APC c.1458C > T assay

From: Correlation between mutations and mRNA expression of APC and MUTYH genes: new insight into hereditary colorectal polyposis predisposition

More than 1.0 SD from the overall mean (<0.99 and >1.53)
Status Within 1 SD Out of 1 SD Total Chi-square or Fisher’s Exact p-value vs control
Controlsb 57 11 68  
APC + polyposis cases 4 4a 8 0.022
APC - polyposis cases 9 4 13 0.214
CRC casesb 30 22 52 0.001
Overall 100 41 141  
  1. aCase GD41, with monoallelic expression, was included in the table among cases deviating more than 1.0 SD from the overall mean
  2. bPreviously published [11]
  3. Bold values indicate statistical significance