Correlation between mutations and mRNA expression of APC and MUTYH genes: new insight into hereditary colorectal polyposis predisposition

Table 4 Distribution of cases and controls at 1.0 SD from the overall mean ASE for APC c.1458C > T assay

More than 1.0 SD from the overall mean (<0.99 and >1.53)
Status	Within 1 SD	Out of 1 SD	Total	Chi-square or Fisher’s Exact p-value vs control
Controls^b	57	11	68
APC + polyposis cases	4	4^a	8	0.022
APC - polyposis cases	9	4	13	0.214
CRC cases^b	30	22	52	0.001
Overall	100	41	141

^aCase GD41, with monoallelic expression, was included in the table among cases deviating more than 1.0 SD from the overall mean
^bPreviously published [11]
Bold values indicate statistical significance

ISSN: 1756-9966