Fig. 6

miR-27b-3p inhibits xenograft tumor growth of GC cells. a and b Photographs of tumors derived from the different groups of nude mice; the graph is representative of tumor growth 21 days after inoculation. c and d Tumor volume and the weight were calculated, and all date are shown as mean ± SD (* P < 0.05). e Western blotting analysis of c-Src/STAT3 signaling pathway related proteins showed upregulation of p-c-Src, p-STAT3, c-Myc and cyclin D1 in miR-27b-3p inhibitor of AGS cell and downregulation of p-c-Src, p-STAT3, c-Myc and cyclin D1 in miR-27b-3p mimics of BGC823 cell, total c-Src and total STAT3 protein level was unchanged