TY - JOUR AU - Siegel, R. AU - Naishadham, D. AU - Jemal, A. PY - 2012 DA - 2012// TI - Cancer statistics, 2012 JO - CA Cancer J Clin VL - 62 UR - https://doi.org/10.3322/caac.20138 DO - 10.3322/caac.20138 ID - Siegel2012 ER - TY - JOUR AU - Tang, Z. Y. AU - Ye, S. L. AU - Liu, Y. K. AU - Qin, L. X. AU - Sun, H. C. AU - Ye, Q. H. PY - 2004 DA - 2004// TI - A decade’s studies on metastasis of hepatocellular carcinoma JO - J Cancer Res Clin Oncol VL - 130 UR - https://doi.org/10.1007/s00432-003-0511-1 DO - 10.1007/s00432-003-0511-1 ID - Tang2004 ER - TY - JOUR AU - Grivennikov, S. I. AU - Greten, F. R. AU - Karin, M. PY - 2010 DA - 2010// TI - Immunity, inflammation, and cancer JO - Cell VL - 140 UR - https://doi.org/10.1016/j.cell.2010.01.025 DO - 10.1016/j.cell.2010.01.025 ID - Grivennikov2010 ER - TY - JOUR AU - Zhang, H. H. AU - Mei, M. H. AU - Fei, R. AU - Liu, F. AU - Wang, J. H. AU - Liao, W. J. PY - 2010 DA - 2010// TI - Regulatory T cells in chronic hepatitis B patients affect the immunopathogenesis of hepatocellular carcinoma by suppressing the anti-tumour immune responses JO - J Viral Hepat VL - 17 UR - https://doi.org/10.1111/j.1365-2893.2010.01269.x DO - 10.1111/j.1365-2893.2010.01269.x ID - Zhang2010 ER - TY - JOUR AU - Kuang, D. M. AU - Zhao, Q. AU - Peng, C. AU - Xu, J. AU - Zhang, J. P. AU - Wu, C. PY - 2009 DA - 2009// TI - Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1 JO - J Exp Med VL - 206 UR - https://doi.org/10.1084/jem.20082173 DO - 10.1084/jem.20082173 ID - Kuang2009 ER - TY - JOUR AU - Hernandez-Gea, V. AU - Toffanin, S. AU - Friedman, S. L. AU - Llovet, J. M. PY - 2013 DA - 2013// TI - Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma JO - Gastroenterology VL - 144 UR - https://doi.org/10.1053/j.gastro.2013.01.002 DO - 10.1053/j.gastro.2013.01.002 ID - Hernandez-Gea2013 ER - TY - JOUR AU - Kuang, D. M. AU - Zhao, Q. AU - Wu, Y. AU - Peng, C. AU - Wang, J. AU - Xu, Z. PY - 2011 DA - 2011// TI - Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma JO - J Hepatol VL - 54 UR - https://doi.org/10.1016/j.jhep.2010.08.041 DO - 10.1016/j.jhep.2010.08.041 ID - Kuang2011 ER - TY - JOUR AU - Li, Y. W. AU - Qiu, S. J. AU - Fan, J. AU - Zhou, J. AU - Gao, Q. AU - Xiao, Y. S. PY - 2011 DA - 2011// TI - Intratumoral neutrophils: a poor prognostic factor for hepatocellular carcinoma following resection JO - J Hepatol VL - 54 UR - https://doi.org/10.1016/j.jhep.2010.07.044 DO - 10.1016/j.jhep.2010.07.044 ID - Li2011 ER - TY - JOUR AU - Gregory, A. D. AU - Houghton, A. M. PY - 2011 DA - 2011// TI - Tumor-associated neutrophils: new targets for cancer therapy JO - Cancer Res VL - 71 UR - https://doi.org/10.1158/0008-5472.CAN-10-2583 DO - 10.1158/0008-5472.CAN-10-2583 ID - Gregory2011 ER - TY - JOUR AU - Li, L. AU - Xu, L. AU - Yan, J. AU - Zhen, Z. J. AU - Ji, Y. AU - Liu, C. Q. PY - 2015 DA - 2015// TI - CXCR2-CXCL1 axis is correlated with neutrophil infiltration and predicts a poor prognosis in hepatocellular carcinoma JO - J Exp Clin Cancer Res VL - 34 UR - https://doi.org/10.1186/s13046-015-0247-1 DO - 10.1186/s13046-015-0247-1 ID - Li2015 ER - TY - JOUR AU - Zhou, S. L. AU - Dai, Z. AU - Zhou, Z. J. AU - Wang, X. Y. AU - Yang, G. H. AU - Wang, Z. PY - 2012 DA - 2012// TI - Overexpression of CXCL5 mediates neutrophil infiltration and indicates poor prognosis for hepatocellular carcinoma JO - Hepatology VL - 56 UR - https://doi.org/10.1002/hep.25907 DO - 10.1002/hep.25907 ID - Zhou2012 ER - TY - JOUR AU - Mano, Y. AU - Shirabe, K. AU - Yamashita, Y. AU - Harimoto, N. AU - Tsujita, E. AU - Takeishi, K. PY - 2013 DA - 2013// TI - Preoperative neutrophil-to-lymphocyte ratio is a predictor of survival after hepatectomy for hepatocellular carcinoma: a retrospective analysis JO - Ann Surg VL - 258 UR - https://doi.org/10.1097/SLA.0b013e318297ad6b DO - 10.1097/SLA.0b013e318297ad6b ID - Mano2013 ER - TY - JOUR AU - Motomura, T. AU - Shirabe, K. AU - Mano, Y. AU - Muto, J. AU - Toshima, T. AU - Umemoto, Y. PY - 2013 DA - 2013// TI - Neutrophil-lymphocyte ratio reflects hepatocellular carcinoma recurrence after liver transplantation via inflammatory microenvironment JO - J Hepatol VL - 58 UR - https://doi.org/10.1016/j.jhep.2012.08.017 DO - 10.1016/j.jhep.2012.08.017 ID - Motomura2013 ER - TY - JOUR AU - Gao, Q. AU - Wang, X. Y. AU - Qiu, S. J. AU - Yamato, I. AU - Sho, M. AU - Nakajima, Y. PY - 2009 DA - 2009// TI - Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinoma JO - Clin Cancer Res VL - 15 UR - https://doi.org/10.1158/1078-0432.CCR-08-1608 DO - 10.1158/1078-0432.CCR-08-1608 ID - Gao2009 ER - TY - JOUR AU - Dong, H. AU - Strome, S. E. AU - Salomao, D. R. AU - Tamura, H. AU - Hirano, F. AU - Flies, D. B. PY - 2002 DA - 2002// TI - Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion JO - Nat Med VL - 8 UR - https://doi.org/10.1038/nm0902-1039c DO - 10.1038/nm0902-1039c ID - Dong2002 ER - TY - JOUR AU - Taube, J. M. AU - Young, G. D. AU - McMiller, T. L. AU - Chen, S. AU - Salas, J. T. AU - Pritchard, T. S. PY - 2015 DA - 2015// TI - Differential Expression of Immune-Regulatory Genes Associated with PD-L1 Display in Melanoma: Implications for PD-1 Pathway Blockade JO - Clin Cancer Res VL - 21 UR - https://doi.org/10.1158/1078-0432.CCR-15-0244 DO - 10.1158/1078-0432.CCR-15-0244 ID - Taube2015 ER - TY - JOUR AU - McClanahan, F. AU - Hanna, B. AU - Miller, S. AU - Clear, A. J. AU - Lichter, P. AU - Gribben, J. G. PY - 2015 DA - 2015// TI - PD-L1 checkpoint blockade prevents immune dysfunction and leukemia development in a mouse model of chronic lymphocytic leukemia JO - Blood VL - 126 UR - https://doi.org/10.1182/blood-2015-01-622936 DO - 10.1182/blood-2015-01-622936 ID - McClanahan2015 ER - TY - JOUR AU - Dovedi, S. J. AU - Illidge, T. M. PY - 2015 DA - 2015// TI - The antitumor immune response generated by fractionated radiation therapy may be limited by tumor cell adaptive resistance and can be circumvented by PD-L1 blockade JO - Oncoimmunology VL - 4 UR - https://doi.org/10.1080/2162402X.2015.1016709 DO - 10.1080/2162402X.2015.1016709 ID - Dovedi2015 ER - TY - JOUR AU - Sznol, M. PY - 2014 DA - 2014// TI - Blockade of the B7-H1/PD-1 pathway as a basis for combination anticancer therapy JO - Cancer J VL - 20 UR - https://doi.org/10.1097/PPO.0000000000000056 DO - 10.1097/PPO.0000000000000056 ID - Sznol2014 ER - TY - JOUR AU - Sznol, M. AU - Chen, L. PY - 2013 DA - 2013// TI - Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer JO - Clin Cancer Res VL - 19 UR - https://doi.org/10.1158/1078-0432.CCR-12-2063 DO - 10.1158/1078-0432.CCR-12-2063 ID - Sznol2013 ER - TY - JOUR AU - Duraiswamy, J. AU - Freeman, G. J. AU - Coukos, G. PY - 2013 DA - 2013// TI - Therapeutic PD-1 pathway blockade augments with other modalities of immunotherapy T-cell function to prevent immune decline in ovarian cancer JO - Cancer Res VL - 73 UR - https://doi.org/10.1158/0008-5472.CAN-13-1550 DO - 10.1158/0008-5472.CAN-13-1550 ID - Duraiswamy2013 ER - TY - JOUR AU - Topalian, S. L. AU - Hodi, F. S. AU - Brahmer, J. R. AU - Gettinger, S. N. AU - Smith, D. C. AU - McDermott, D. F. PY - 2012 DA - 2012// TI - Safety, activity, and immune correlates of anti-PD-1 antibody in cancer JO - N Engl J Med VL - 366 UR - https://doi.org/10.1056/NEJMoa1200690 DO - 10.1056/NEJMoa1200690 ID - Topalian2012 ER - TY - JOUR AU - Brahmer, J. R. AU - Tykodi, S. S. AU - Chow, L. Q. AU - Hwu, W. J. AU - Topalian, S. L. AU - Hwu, P. PY - 2012 DA - 2012// TI - Safety and activity of anti-PD-L1 antibody in patients with advanced cancer JO - N Engl J Med VL - 366 UR - https://doi.org/10.1056/NEJMoa1200694 DO - 10.1056/NEJMoa1200694 ID - Brahmer2012 ER - TY - JOUR AU - Massari, F. AU - Santoni, M. AU - Ciccarese, C. AU - Santini, D. AU - Alfieri, S. AU - Martignoni, G. PY - 2015 DA - 2015// TI - PD-1 blockade therapy in renal cell carcinoma: current studies and future promises JO - Cancer Treat Rev VL - 41 UR - https://doi.org/10.1016/j.ctrv.2014.12.013 DO - 10.1016/j.ctrv.2014.12.013 ID - Massari2015 ER - TY - JOUR AU - Wu, K. AU - Kryczek, I. AU - Chen, L. AU - Zou, W. AU - Welling, T. H. PY - 2009 DA - 2009// TI - Kupffer cell suppression of CD8+ T cells in human hepatocellular carcinoma is mediated by B7-H1/programmed death-1 interactions JO - Cancer Res VL - 69 UR - https://doi.org/10.1158/0008-5472.CAN-09-0901 DO - 10.1158/0008-5472.CAN-09-0901 ID - Wu2009 ER - TY - JOUR AU - Bankey, P. E. AU - Banerjee, S. AU - Zucchiatti, A. AU - De, M. AU - Sleem, R. W. AU - Lin, C. F. PY - 2010 DA - 2010// TI - Cytokine induced expression of programmed death ligands in human neutrophils JO - Immunol Lett VL - 129 UR - https://doi.org/10.1016/j.imlet.2010.01.006 DO - 10.1016/j.imlet.2010.01.006 ID - Bankey2010 ER - TY - JOUR AU - Bowers, N. L. AU - Helton, E. S. AU - Huijbregts, R. P. AU - Goepfert, P. A. AU - Heath, S. L. AU - Hel, Z. PY - 2014 DA - 2014// TI - Immune suppression by neutrophils in HIV-1 infection: role of PD-L1/PD-1 pathway JO - PLoS Pathog VL - 10 UR - https://doi.org/10.1371/journal.ppat.1003993 DO - 10.1371/journal.ppat.1003993 ID - Bowers2014 ER - TY - JOUR AU - McNab, F. W. AU - Berry, M. P. AU - Graham, C. M. AU - Bloch, S. A. AU - Oni, T. AU - Wilkinson, K. A. PY - 2011 DA - 2011// TI - Programmed death ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosis JO - Eur J Immunol VL - 41 UR - https://doi.org/10.1002/eji.201141421 DO - 10.1002/eji.201141421 ID - McNab2011 ER - TY - JOUR AU - Kee, K. M. AU - Wang, J. H. AU - Lee, C. M. AU - Chen, C. L. AU - Changchien, C. S. AU - Hu, T. H. PY - 2007 DA - 2007// TI - Validation of clinical AJCC/UICC TNM staging system for hepatocellular carcinoma: analysis of 5,613 cases from a medical center in southern Taiwan JO - Int J Cancer VL - 120 UR - https://doi.org/10.1002/ijc.22616 DO - 10.1002/ijc.22616 ID - Kee2007 ER - TY - JOUR AU - Eruslanov, E. B. AU - Bhojnagarwala, P. S. AU - Quatromoni, J. G. AU - Stephen, T. L. AU - Ranganathan, A. AU - Deshpande, C. PY - 2014 DA - 2014// TI - Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer JO - J Clin Invest VL - 124 UR - https://doi.org/10.1172/JCI77053 DO - 10.1172/JCI77053 ID - Eruslanov2014 ER - TY - JOUR AU - Sullivan, K. M. AU - Groeschl, R. T. AU - Turaga, K. K. AU - Tsai, S. AU - Christians, K. K. AU - White, S. B. PY - 2014 DA - 2014// TI - Neutrophil-to-lymphocyte ratio as a predictor of outcomes for patients with hepatocellular carcinoma: a Western perspective JO - J Surg Oncol VL - 109 UR - https://doi.org/10.1002/jso.23448 DO - 10.1002/jso.23448 ID - Sullivan2014 ER - TY - JOUR AU - Piccard, H. AU - Muschel, R. J. AU - Opdenakker, G. PY - 2012 DA - 2012// TI - On the dual roles and polarized phenotypes of neutrophils in tumor development and progression JO - Crit Rev Oncol Hematol VL - 82 UR - https://doi.org/10.1016/j.critrevonc.2011.06.004 DO - 10.1016/j.critrevonc.2011.06.004 ID - Piccard2012 ER - TY - JOUR AU - Fridlender, Z. G. AU - Sun, J. AU - Kim, S. AU - Kapoor, V. AU - Cheng, G. AU - Ling, L. PY - 2009 DA - 2009// TI - Polarization of tumor-associated neutrophil phenotype by TGF-beta: “N1” versus “N2” TAN JO - Cancer Cell VL - 16 UR - https://doi.org/10.1016/j.ccr.2009.06.017 DO - 10.1016/j.ccr.2009.06.017 ID - Fridlender2009 ER -