Fig. 1

Neutrophils predominantly infiltrated in the peritumoural tissue in patients with HCC. a, b Representative images were shown for CD66b and CD3 immunohistochemical staining of tumour tissues from patients with HCC. A high density of CD66b⁺ neutrophils is correlated with a low density of CD3⁺ T cells in the tumour tissue. c Infiltrating CD66b⁺ neutrophils and CD3⁺ T cells in intratumoural tissue and peritumoural tissues that were analysed by paired t-Test (P < 0.001 for both). d The neutrophil/T cell ratio (NLR) in intratumoural tissue and peritumoural tissues that were analysed by paired t-Test (P < 0.001 for both). e Correlation of the number of CD66b⁺ neutrophils and CD3⁺ T cells in peritumoural tissues and intratumoural tissues in patients with HCC as analyzed by Pearson correlation analysis and linear regression analysis (r = −0.7902, P < 0.001 and r = 0.2890, P = 0.0974, respectively)