Fig. 3

Plasma cell tumors and high-grade splenic marginal zone lymphoma. a, b Lymph node sections from two mice (from different litters) stained with H&E (magnification 40x). a. Low-grade tumor with mature plasma cells. b Higher grade tumor dominated by plasmablasts (red arrows) (c) Low power view of a spleen stained with H&E showing small follicles surrounded by multiple layers of pale-staining marginal zone cells (red arrows) (magnification 4x). d Cells in the marginal zone have acquired centroblastic cytology (red arrows) (magnification 40x)