Fig. 1
From: Karyopherin alpha 2 is a novel prognostic marker and a potential therapeutic target for colon cancer
Analysis of KPNA2 expression in human colon cancer tissues. a Real-time quantitative PCR analysis of KPNA2 expression in human colon cancer tissues and paired normal tissues. KPNA2 mRNA level was normalized using GAPDH expression. A logarithmic scale of 2-ΔΔCT was used to represent the fold-change. The dashed line represents a 2-fold change normalized to paired normal tissues. b Western blot analysis was performed to assess KPNA2 protein levels in 4 representative cases of colon cancer specimens. c KPNA2 protein is higher in tumor tissues than in paired adjacent normal mucosa. ‘N’ represents normal tissue; ‘T’ represents tumor tissue. ‘*’ p < 0.001