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Table 4 Multivariate analysis of the DFS and OS in 195 colon cancer patients

From: Karyopherin alpha 2 is a novel prognostic marker and a potential therapeutic target for colon cancer

Variable DFS OS
  HR 95 % CI p HR 95 % CI p
AJCC stage
(I/II vs. III/IV) 2.669 1.491–4.779 0.001* 9.030 1.198–68.048 0.033*
N stage 2.890 1.696–4.926 <0.001* 2.528 1.177–5.426 0.017*
M stage 4.261 1.225–14.820 0.023* 5.711 1.586–20.568 0.008*
Vascular invasion 1.946 0.955–3.963 0.067 1.685 0.687–4.130 0.254
KPNA2 expression 1.681 1.170–2.416 0.005* 2.770 1.314–5.837 0.007*
  1. HR hazard ration, CI confidence interval. *p < 0.005 indicates that the lower limit of the 95 % CI of HR is >1