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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: LDOC1 inhibits proliferation and promotes apoptosis by repressing NF-κB activation in papillary thyroid carcinoma

Fig. 3

LDOC1 overexpression in the PTC-derived cell line TPC-1 by means of lentivirus-mediated cDNA expression. a LDOC1 expression in PTC cell lines (BCPAP and TPC-1) and normal thyroid tissue (n = 47). Some representative results of immunoblotting are shown. b Representative images of TPC-1 cells transduced with either a lentiviral vector carrying the LDOC1 cDNA (Lv-LDOC1) or the empty lentiviral vector (Lv-NC; negative control, GFP only). c Flow cytometry analysis of the efficiency of lentivirus-mediated cDNA transduction. d LDOC1 overexpression in TPC-1 cells validated using qRT-PCR and western blotting. LDOC1 expression was normalized relative to the level of the loading control β-actin. **P < 0.01 and ***P < 0.001

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