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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo

Fig. 3

FOXO3a cytoplasmic and nuclear protein expression in MCF-7 and MDA-MB231 cells after vernodalin treatment. MCF-7 and MDA-MB231 cells were treated with vernodalin for the indicated time periods, and the subcellular fractions were then isolated and immunoblotted for FOXO3a. Lamin B1 and GAPDH were used as markers of the nucleus and cytoplasm respectively. Vernodalin treatment caused the translocation of FOXO3a from the cytoplasm to the nucleus. Results are representative of three independent experiments

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