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Table 1 Treatment effect of vernodalin and TAM on animal body weight (g), tumor volume (mm3) and tumor reduction percentage (%) in LA-7-induced breast cancer rats

From: Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo

Group Treatment groups Body weight (g) Tumor volume (mm3) Tumor reduction percentage (%)
I NC 247.3 ± 1.5 0 0 %
II TC 213.13 ± 1.32 2143 ± 363 0 %
III TT (1 mg/kg vernodalin) 219.14 ± 7.2 1182 ± 352* 44.84 %
IV TT (10 mg/kg vernodalin) 221.57 ± 5 524 ± 261* 75.6 %
V TT (1 mg/kg TAM) 224.88 ± 5.7 562 ± 145* 73.78 %
  1. Each value represents mean ± S.D. of given number of animals (n = 5). “*” denotes statistically significant at p < 0.05 compared to control group