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Table 1 Clinical characteristics and its relationship with CCR7/ MUC1 expression

From: CCL21-CCR7 promotes the lymph node metastasis of esophageal squamous cell carcinoma by up-regulating MUC1

Clinical characteristic CCR7 positive expression P value MUC1 positive expression P value
Gender   0.45   0.85
 Male 69/116   74/116  
 Female 19/37   23/37  
Age(year)   0.86   0.2
 ≥50 63/108   72/108  
 <50 25/45   25/45  
Length of tumor(cm)   0.98   0.08
 <3 cm 20/35   20/35  
 3 ~ 5 cm 42/72   50/72  
 >5 cm 26/46   27/46  
Invasion depth   0.27   0.07
 T1 11/25   11/25  
 T2 44/76   49/76  
 T3 + T4a 33/52   37/52  
Lymphatic metastasis   0.01   <0.001
 Yes 60/89   67/89  
 No 28/64   30/64  
 Differentiation   0.14   0.42
 Well/moderate 34/67   35/67  
 Low 54/86   62/86  
 Weight loss   0.5   0.16
 Yes 15/23   18/23  
 No 73/130   79/130  
Regional lymphatic recurrence   0   <0.001
 Yes 54/78   61/78  
 No 41/75   39/75