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Table 2 Clinical characteristics and its relationship with CCR7 & MUC1 expression

From: CCL21-CCR7 promotes the lymph node metastasis of esophageal squamous cell carcinoma by up-regulating MUC1

Clinical characteristic

CCR7+ MUC1+

CCR7+ MUC1-

CCR7- MUC1+

CCR7- MUC1-

P value

Gender

    

0.46

 Male

57/116

12/116

17/116

30/116

 

 Female

14/37

5/37

9/37

9/37

 

Age(year)

    

0.61

 ≥50

52/108

11/108

20/108

25/108

 

 <50

19/45

6/45

6/45

14/45

 

Length of tumor(cm)

    

0.65

 <3 cm

16/35

4/35

4/35

11/35

 

 3 ~ 5 cm

34/72

8/72

16/72

14/72

 

 >5 cm

21/46

5/46

6/46

14/46

 

Invasion depth

    

0.170

 T1

9/25

2/25

2/25

12/25

 

 T2

35/76

9/76

14/76

18/76

 

 T3 + T4a

27/52

6/52

10/52

9/52

 

Lymphatic metastasis

    

<0.001

 Yes

53/89

7/89

18/89

11/89

 

 No

18/64

10/64

8/64

28/64

 

Differentiation

    

0.06

 Well/moderate

26/67

8/67

9/67

24/67

 

 Low

45/86

9/86

17/86

15/86

 

 Weight loss

    

0.2

 Yes

12/23

3/23

6/23

2/23

 

 No

59/130

14/130

20/130

37/130

 

Regional lymphatic recurrence

    

<0.001

 Yes

46/78

8/78

15/78

9/78

 

 No

25/75

9/75

11/75

30/75

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