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Table 2 Clinical characteristics and its relationship with CCR7 & MUC1 expression

From: CCL21-CCR7 promotes the lymph node metastasis of esophageal squamous cell carcinoma by up-regulating MUC1

Clinical characteristic CCR7+ MUC1+ CCR7+ MUC1- CCR7- MUC1+ CCR7- MUC1- P value
Gender      0.46
 Male 57/116 12/116 17/116 30/116  
 Female 14/37 5/37 9/37 9/37  
Age(year)      0.61
 ≥50 52/108 11/108 20/108 25/108  
 <50 19/45 6/45 6/45 14/45  
Length of tumor(cm)      0.65
 <3 cm 16/35 4/35 4/35 11/35  
 3 ~ 5 cm 34/72 8/72 16/72 14/72  
 >5 cm 21/46 5/46 6/46 14/46  
Invasion depth      0.170
 T1 9/25 2/25 2/25 12/25  
 T2 35/76 9/76 14/76 18/76  
 T3 + T4a 27/52 6/52 10/52 9/52  
Lymphatic metastasis      <0.001
 Yes 53/89 7/89 18/89 11/89  
 No 18/64 10/64 8/64 28/64  
Differentiation      0.06
 Well/moderate 26/67 8/67 9/67 24/67  
 Low 45/86 9/86 17/86 15/86  
 Weight loss      0.2
 Yes 12/23 3/23 6/23 2/23  
 No 59/130 14/130 20/130 37/130  
Regional lymphatic recurrence      <0.001
 Yes 46/78 8/78 15/78 9/78  
 No 25/75 9/75 11/75 30/75