Fig. 2

Gab2 promotes CRC cells migration and invasion in vitro. a Expression of Gab2 in four human CRC cell lines relative to the normal human intestinal epithelial cell line FHC was detected by qRT-PCR. b Western blot analysis of Gab2 expression in different CRC cell lines. c Migration and invasion assay of SW480-NC and SW480-Gab2 cells. d Migration and invasion of SW480-NC and SW480-Gab2 cells were quantitatively analyzed. Columns are the average of three independent experiments ± SEM. e and f Migration and invasion assay of SW620-si-Ctrl and SW620-Gab2si cells (two clones, c and d). ***P < 0.001