Fig. 7From: Tumor-associated macrophages correlate with the clinicopathological features and poor outcomes via inducing epithelial to mesenchymal transition in oral squamous cell carcinomaTAMs induce the cancer cells undergo epithelial to mesenchymal transition (EMT). a The HN4, HN6 and SCC9 cells presented typical cobblestone and epithelial-like appearances. The HN4-M, HN6-M and SCC9-M cells were scattered and spindle shaped, exhibited fibroblast-like appearances. The photographs were taken at 40x magnification. b The relative mRNA expression levels of E-cadherin, and vimentin was performed by real-time RT-PCR. The housekeeping gene GAPDH was used as the control. The data were reported as mean ± SD. c The EMT-related proteins E-cadherin and vimentin were examined by the Western blot, β-actin was used as a loading control. The data were reported as mean ± SD. * P < 0.05, ** P < 0.01Back to article page