Skip to main content

Table 4 Relationship between CD68, CD163 expression levels of tumors and clinical variables

From: Tumor-associated macrophages correlate with the clinicopathological features and poor outcomes via inducing epithelial to mesenchymal transition in oral squamous cell carcinoma

Variable No. CD68 CD163
N L H P N L H P
Sex      0.081     0.008
 Male 74 15 19 40   35 25 14  
 Female 53 6 8 39   13 18 22  
Age (years)      0.668     0.642
 ≤50 26 5 4 17   8 9 9  
 >50 101 16 23 62   40 34 27  
Tumor location      0.324     0.405
 Tongue 52 10 12 30   20 17 15  
 Gingiva 26 3 2 21   8 11 7  
 Buccal mucosa 31 3 8 20   11 9 11  
 Lip 4 2 1 1   4 0 0  
 Floor of the mouth 2 0 1 1   0 1 1  
 Others 12 3 3 6   5 5 2  
Tumor size      0.419     0.124
 T1 21 5 3 13   9 4 8  
 T2 68 9 14 45   23 24 21  
 T3 26 4 5 17   14 7 5  
 T4 12 3 5 4   2 8 2  
Lymph node metastasis      0.044     0.098
 N0 72 15 19 38   33 22 17  
 N (+) 55 6 8 41   15 21 19  
Metastasis      0.542     0.535
 M0 125 21 27 77   48 42 35  
 M (+) 2 0 0 2   0 1 1  
Clinical stage      0.564     0.114
 I 12 4 2 6   7 2 3  
 II 42 7 10 25   17 14 11  
 III 34 4 7 23   14 9 11  
 IV 39 6 8 25   10 18 11  
Pathological grade      0.986     0.537
 I 76 12 17 47   31 25 20  
 II 42 8 6 28   15 16 11  
 III 9 1 4 4   2 2 5  
Recurrence      0.870     0.01
 No 83 14 16 53   35 32 16  
 Yes 42 7 11 24   13 10 19  
 Lost 2 0 0 2   0 1 1  
Follow-up      0.560     0
 Live 91 16 17 58   41 33 17  
 Dead 33 5 10 18   7 9 17  
 Lost 3 0 0 3   0 1 2  
  1. No., number of patients; N, negative; L low expression; H, high expression. N0, no lymph node metastasis; N (+), node metastasis. M0, no metastasis; M(+), metastasis
  2. Bold values signify P < 0.05