Tumor-associated macrophages correlate with the clinicopathological features and poor outcomes via inducing epithelial to mesenchymal transition in oral squamous cell carcinoma

Table 5 Relationship between E-cadherin, vimentin expression levels of tumors and clinical variables

Variable	No.	E-cadherin				Vimentin
Variable	No.	N	L	H	P	N	L	H	P
Sex					0.990				0.205
Male	74	16	21	37		37	22	15
Female	53	12	15	26		19	17	17
Age (years)					0.257				0.383
≤50	26	7	4	15		12	10	4
>50	101	21	32	48		44	29	28
Tumor location					0.444				0.345
Tongue	52	13	12	27		26	16	10
Gingiva	26	3	6	17		12	10	4
Buccal mucosa	31	9	11	11		10	8	13
Lip	4	1	1	2		1	2	1
Floor of the mouth	2	1	1	0		2	0	0
Others	12	1	5	6		5	3	4
Tumor size					0.848				0.819
T1	21	3	7	11		10	6	5
T2	68	18	19	31		27	24	17
T3	26	5	7	14		12	5	9
T4	12	2	3	7		7	4	1
Lymph node metastasis					0.150				0.010
N0	72	20	17	35		40	19	13
N (+)	55	8	19	28		16	20	19
Metastasis					0.678				0.050
M0	125	28	35	62		56	39	30
M (+)	2	0	1	1		0	0	2
Clinical stage					0.071				0.046
I	12	3	1	8		9	2	1
II	42	15	10	17		21	12	9
III	34	4	12	18		13	10	11
IV	39	6	13	20		13	15	11
Pathological grade					0.441				0.001
I	76	16	19	41		40	25	11
II	42	11	13	18		15	13	14
III	9	1	4	4		1	1	7
Recurrence					0.922				0.05
No	83	18	24	41		43	24	16
Yes	42	9	12	21		13	14	15
Lost	2	1	0	1		0	1	1
Follow-up					0.747				0.014
Live	91	18	27	46		47	27	17
Dead	33	9	9	15		9	11	13
Lost	3	1	0	2		0	1	2

No., number of patients; N, negative; L low expression; H, high expression; N0, no nodal metastasis; N(+), nodal metastasis. M0, no metastasis; M(+), metastasis
Bold values signify P < 0.05

ISSN: 1756-9966