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Table 6 Relationship between E-cadherin, vimentin expression levels of the tumors invasive front and clinical variables

From: Tumor-associated macrophages correlate with the clinicopathological features and poor outcomes via inducing epithelial to mesenchymal transition in oral squamous cell carcinoma

Variable No. E-cadherin Vimentin
N L H P N L H P
Sex      0.554     0.024
 Male 74 20 28 26   37 18 19  
 Female 53 15 24 14   19 8 26  
Age (years)      0.988     0.209
 ≤50 26 7 11 8   12 8 6  
 >50 101 28 41 32   44 18 39  
Tumor location      0.123     0.508
 Tongue 52 15 21 16   26 9 17  
 Gingiva 26 6 6 14   12 7 7  
 Buccal mucosa 31 11 15 5   10 6 15  
 Lip 4 1 1 2   1 2 1  
 Floor of the mouth 2 1 1 0   2 0 0  
 Others 12 1 8 3   5 2 5  
Tumor size      0.970     0.818
 T1 21 5 8 8   10 4 7  
 T2 68 21 28 19   27 16 25  
 T3 26 6 13 7   12 4 10  
 T4 12 3 3 6   7 2 3  
Lymph node metastasis      0.236     0.003
 N0 72 23 25 24   40 15 17  
 N (+) 55 12 27 16   16 11 28  
Metastasis      0.665     0.159
 M0 125 35 51 39   56 26 43  
 M (+) 2 0 1 1   0 0 2  
Clinical stage      0.236     0.043
 I 12 3 3 6   9 2 1  
 II 42 17 13 12   21 8 13  
 III 34 5 19 10   13 6 15  
 IV 39 10 17 12   13 10 16  
Pathological grade      0.659     0.007
 I 76 20 29 27   40 16 20  
 II 42 13 20 9   15 10 17  
 III 9 2 3 4   1 0 8  
Recurrence      0.460     0.01
 No 83 22 32 29   43 19 21  
 Yes 42 12 20 10   13 6 23  
 Lost 2 1 0 1   0 1 1  
Follow-up      0.301     0.001
 Live 91 22 39 30   47 21 23  
 Dead 33 12 13 8   9 4 20  
 Lost 3 1 0 2   0 1 2  
  1. No., number of patients; N, negative; L low expression; H, high expression. N0, no nodal metastasis; N(+), nodal metastasis. M0, no metastasis; M(+), metastasis
  2. Bold values signify P < 0.05
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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