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Table 8 Univariate cox regression analysis of overall survival

From: Tumor-associated macrophages correlate with the clinicopathological features and poor outcomes via inducing epithelial to mesenchymal transition in oral squamous cell carcinoma

covariate P-value Risk ratio 95 % CI
Sex (male, female) 0.4 1.35 (0.655, 2.043)
Age (≤50 or younger,>50) 0.13 2.49 (1.300, 3.680)
Tumor location Post1 0.75 1.16 (0.244, 2.082)
Tumor location Post2 0. 448 1.38 (0.551, 2.201)
Tumor location Post3 0.98 0 (−1242.048, 1242.048)
Tumor location Post4 0.99 0 (−1596.148, 1596.148)
Tumor location Post5 0.77 0.8 (−0.692, 2.288)
Tumor size (T1-T4) 0.45 1.18 (0.757, 1.595)
Nodal metastasis (N0, N(+)) 0.44 1.31 (0.618, 2.006)
Metastasis (M0, M(+)) 0.69 0.05 (0.760, 1.470)
Clinical stage (I, II, III, IV) 0.55 1.12 (1.146, 2.200)
Pathological grade 0.06 1.67 (0.244, 2.082)
CD68+ macrophages counts in tumor nest (Low, High) 0.01 3.08 (2.236, 3.914)
CD68+ macrophages counts in tumor stroma (Low, High) 0.3 0.69 (−0.010, 1.390)
CD163+ macrophages counts in tumor nest (Low, High) 0.02 2.83 (1.991, 3.669)
CD163+ macrophages counts in tumor stroma (Low, High) 0.48 0.78 (0.085, 1.473)
CD68 expression in tumor (Negative, Low, High) 0.97 1.01 (0.555, 1.465)
CD163 expression in tumor (Negative, Low, High) 0 2.2 (1.735, 2.667)
E-cadherin expression in tumor (Negative, Low, High) 0.61 0.89 (0.465, 1.323)
E-cadherin expression at the invasive front of tumor (Negative, Low, High) 0.19 0.74 (0.280, 1.1937)
Vimentin expression in tumor (Negative, Low, High) 0.01 1.79 (1.373, 2.207)
Vimentin expression at the invasive front of tumor (Negative, Low, High) 0 1.88 (1.474, 2.295)
  1. Bold values signify P < 0.05