Key molecules | score |
---|
FOS | 26 |
JUNB | 23 |
FOSL1 | 21 |
PPARG | 21 |
IRF8 | 20 |
IRF1 | 19 |
CBP | 18 |
IRF4 | 18 |
ISGF3G | 17 |
IKK-beta | 16 |
FOXA2 | 14 |
IRF7 | 14 |
NR3C1 | 14 |
JUND | 13 |
Src-isoform1 | 13 |
IRF2 | 12 |
beta-catenin | 11 |
c-Myc-isoform1 | 11 |
MKK4beta | 11 |
p38alpha | 11 |
- Microarray data were loaded into the ExPlainâ„¢ pathway search tool and key nodes were searched in the upstream pathways. Each key node is assigned a score based on its connectivity of the pathways. Molecules with higher score could be considered as key factors regulating the pathways related with distant metastasis of HNSCC