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Table 1 Significant fold changes in serum miRNAs in lung cancer patients before and after radiotherapy analyzed by miRNA microarray

From: Radiation-induced miR-208a increases the proliferation and radioresistance by targeting p21 in human lung cancer cells

miRNA ID

AVG ∆Ct

2^-∆Ct

Fold difference

Fold up- or down- regulation

Regulation

(Ct(GOI)-Ave Ct(HKG))

After RT

Before RT

After RT

Before RT

After RT/Before RT

p value

After RT/Before RT

hsa-miR-29b-3p

4.929

3.756

0.033

0.074

0.444

0.002

−2.254

Down

hsa-miR-223-3p

−4.307

−4.850

19.799

28.833

0.687

0.004

−1.456

Down

hsa-miR-126-3p

−1.855

−2.132

3.618

4.382

0.826

0.008

−1.211

Down

hsa-miR-26b-Sp

–0.080

–0.436

1.057

1.353

0.781

0.025

–1.280

Down

hsa-miR-208a

13.010

14.133

0.000

0.000

2.179

0.030

2.179

Up

hsa-miR-200a-3p

9.266

7.497

0.002

0.006

0.293

0.038

–3.408

Down

hsa-miR-15b-Sp

1.646

0.935

0.319

0.523

0.611

0.039

−1.637

Down

hsa-Iet-7c

3.984

3.518

0.063

0.087

0.724

0.041

−1.382

Down

hsa-miR-382-Sp

7.302

6.578

0.006

0.010

0.605

0.042

−1.652

Down

hsa-Iet-7i-3p

8.801

8.142

0.002

0.004

0.634

0.049

−1.579

Down