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Table 3 Relationship between UPF1 expression and clinicopathologic parameters of HCC patients

From: The human RNA surveillance factor UPF1 regulates tumorigenesis by targeting Smad7 in hepatocellular carcinoma

Characteristics

Number of cases

UPF1 expression

P value

Low(n = 25)

High(n = 25)

Age(years)

   

0.152

  ≥ 65

29

17

12

  < 65

21

8

13

Gender

   

0.157

 Male

40

18

22

 Female

10

7

3

Tumor size

   

0.364

  ≥ 5 cm

32

19

13

  < 5 cm

18

6

12

Edmondson-Steiner

   

0.015*

 I-II

34

21

13

 III-IV

16

4

12

HBV infection

   

0.088

 Postive

39

17

22

 Negtive

11

8

3

BCLC stage

   

0.020*

 A

42

24

18

 B + C

8

1

7

Liver cirrhosis

   

0.225

 Yes

34

15

19

 No

16

10

6

Serum AFP(μg/L)

  

0.771

  ≥ 400

31

16

15

  < 400

19

9

10

Tumor number

   

0.747

 Singular

37

18

19

 Multifocal

13

7

6

PVTT

   

0.031*

 Yes

15

4

11

 No

35

21

14

  1. Barcelona Clinic Liver Cancer stage: BCLC
  2. Portal vein tumor thrombus: PVTT
  3. *p < 0.05