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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: MiR-548c impairs migration and invasion of endometrial and ovarian cancer cells via downregulation of Twist

Fig. 2

MiR-548c inhibits proliferation, migration and invasion of EC and OC cells. a Relative expression of miR-548c in two EC cell lines (RL95-2 and HEC-1) and OC cell lines (OVCAR3 and SKOV-3 was determined by qPCRs. Data is presented as the fold-change in expression compared with RL95-2. b qPCR analysis of miR-548c expression in RL95-2 and OVCAR3 cells transfected with anti-miR-548c inhibitor (anti-548c) or control inhibitor (anti-ctr). c miR-548c levels were measured by qPCRs in HEC-1 or SKOV-3 cells after overexpression of pre-miR-548c mimic (pre-548c) or control mimic (pre-ctr). Cell proliferation assay (d), cell apoptosis assay (e), transwell migration (f) and matrigel invasion (g) assays were performed in indicated cells after knockdown or overexpression of miR-548c, respectively. h Representative images from cell migration and invasion assays performed in SKOV-3 cells. ** P < 0.01

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