Fig. 3

miR-106b promoted the migration of HeLa cells tested by scratch and transwell assay. HeLa cells were transfected with a miR-106b inhibitor (anti-miR-106b) at 100 nm and b miR-106b mimic(miR-106b) at 50 nm. Scratch assay of cell migration with c miR-106b knockdown and d miR-106b overexpression. Scratched cells were observed and photographed at 0 and 24 h under a microscope. Data are mean ± SEM(n = 3).*P < 0.05,**P < 0.01 compared to control. Transwell migration assay with e miR-106b knockdown and f miR-106b overexpression. Cells were transfected with miR-106b inhibitor(anti-miR-106b) and miR-106b control inhibitor (anti-NC). The cells on the transwell chambers were fixed, dyed, observed and photographed after culture for 24 h. Data are mean ± SEM(n = 3). *P < 0.05 compared to control