Fig. 6

Immunohistochemical staining of HOXA1 expression in normal and gastric cancer tissues. HOXA1 staining was observed mainly in the nuclei of GC cells and in the cytoplasm. HOXA1 expression was much higher in the GC tissues than in the adjacent normal mucosae. Normal gastric tissue showing negative HOXA1 expression (a); Positive HOXA1 staining in moderately differentiated GC tissue (b), signet ring cell carcinoma (c) and metastatic lymph nodes (d). Original magnification, 200× (400× for inset images)