Elevated HOXA1 expression correlates with accelerated tumor cell proliferation and poor prognosis in gastric cancer partly via cyclin D1

Table 2 Relationship between clinicopathologic parameters and HOXA1 or cyclin D1 protein expression in gastric cancer (n = 264)

Characteristics	Total	HOXA1 expression		P value	Cyclin D1 expression		P value
Characteristics	Total	Negative (120)	Positive (144)	P value	Negative (127)	Positive (137)	P value
Age(years)				0.457			0.845
<65	121	58	63		59	62
≥65	143	62	81		68	75
Gender				0.095			0.712
Male	157	78	79		77	80
Female	107	42	65		50	57
T stage				0.040*			0.816
T1	76	44	32		38	38
T2	42	20	22		22	20
T3	118	47	71		53	65
T4	28	9	19		14	14
N stage				0.004*			0.179
N0	116	67	49		56	60
N1	91	35	56		48	43
N2	40	13	27		19	21
N3	17	5	12		4	13
M stage				0.355			0.751
M0	254	117	137		123	131
M1	10	3	7		4	6
UICC stage				<0.001*			0.400
I	95	54	41		49	46
II	48	28	20		24	24
III	89	28	61		43	46
IV	32	10	22		11	21
Differentiation				<0.001*			0.044*
High	47	33	14		30	17
Moderate	42	20	22		21	21
Low	175	67	108		76	99

ISSN: 1756-9966