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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: MiR-130a-3p regulates cell migration and invasion via inhibition of Smad4 in gemcitabine resistant hepatoma cells

Fig. 2

Smad4 is associated with miR-130a-3p expression. a Top panel: Real-time RT-PCR assay was performed to detect the mRNA level of Smad4 in HCC GR cells treated with miR-130a-3p mimics. miR-130a-3p was measured by miRNA real-time RT-PCR in HCC GR cells after miR-130a-3p mimic transfection. Bottom panel: Real-time RT-PCR assay was performed to detect the mRNA level of Smad4 in HCC cells treated with miR-130a-3p inhibitor. miR-130a-3p was measured by miRNA real-time RT-PCR in HCC cells after miR-130a-3p inhibitor treatment. *p < 0.05, vs control. b Left panel: Western blotting analysis was conducted to measure the expression of Smad4 in HCC cells treated with miR-130a-3p inhibitor and in HCC GR cells treated with miR-130a-3p mimic. Right panel: Quantitative results are illustrated for left panel

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