Fig. 3

HIF-2α promoted cell migration and invasion. a Cell invasion was detected by the Transwell assay. Representative images of cell invasion captured under an inverted microscope (original magnifiation, ×200). The data represent the means ± SD of 5 experiments. **P < 0.01. b Cell migration was detected by the wound scrape assay. Representative images of cell migration in the wound scrape model at 0, 24 h and 48 h are shown; original magnifiation, ×100. The data represent the means ± SD of three experiments. *P < 0.05