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Table 1 Expression of HIF-2α and E-cadherin, and the relation with the clinicopathologic features in pancreatic carcinoma

From: HIF-2α promotes epithelial-mesenchymal transition through regulating Twist2 binding to the promoter of E-cadherin in pancreatic cancer

Variables   HIF-2α   E-cadherin  
No. Positive Negative P-value Positive Negative P-value
Gender     0.306    0.424
 Male 42 26 16   13 29  
 Female 28 21 7   6 22  
Age (years)     1.000    0.107
  ≤ 65 41 28 13   8 33  
  > 65 29 19 10   11 18  
Tumor location     0.569    0.226
 Head 52 36 16   12 40  
 Body and tail 18 11 7   7 11  
Tumor size (cm)     0.122    0.414
  ≤ 2 27 15 12   9 18  
  > 2 43 32 11   10 33  
Differentiation     0.026    0.784
 Well 8 3 5   3 5  
 Moderate 17 9 8   5 12  
 Poor 45 35 10   11 34  
Clinical stage     0.017    0.579
 I 25 12 13   8 17  
 II 45 35 10   11 34  
Lymph node Metastasis        
 Yes 38 30 8 0.040 5 33 0.006
 No 32 17 15   14 18