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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Atorvastatin (Lipitor) attenuates the effects of aspirin on pancreatic cancerogenesis and the chemotherapeutic efficacy of gemcitabine on pancreatic cancer by promoting M2 polarized tumor associated macrophages

Fig. 1

The representative pictures of DMBA-induced pancreatic cancerogenesis process from chronic pancreatitis (CP) to PanIN (pancreatic intradutal neoplasia) and invasive pancreatic cancer. a Normal pancreas, H&E, ×40; b chronic pancreatitis: the acinar atrophy and stroma hyperplasia, H&E, ×40. c. PanIN-1: the columnar cells with a papillary intraductal arrangements, H&E, ×100. d PanIN-2: the papillary pseudostratified and hyper chromatic lesions, H&E, ×100; e PanIN-3: the severe cellular atypia and cribriform architecture, H&E, ×100; f Invasive pancreatic cancer: the spare pancreatic cancer cells in the stroma, H&E, ×200. (Blue arrows indicate representative lesions)

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