UHRF1 overexpression is involved in cell proliferation and biochemical recurrence in prostate cancer after radical prostatectomy

Table 1 Correlation between UHRF1 protein expression and clinicopathologic features in PCa patients after RP

Features	UHRF1 protein expression		P-Value
Features	Negative	Positive	P-Value
^aAge at Surgery (n = 225)
Median (Range)	68.00 (65.55-67.81)	67.00 (65.28-67.78)	0.832
Mean	66.68	66.50	0.832
^bPathological Stage (pT) (n= 225)*			0.028
pT2-pT3a	97	73
pT3b	22	33
^cLymph Node Status (n= 225)			0.143
Positive	7	12
Negative	112	94
^cTumor Margins (n= 225)			0.825
Positive	20	19
Negative	99	87
^cCapsular Invasion (n= 225)			0.116
No Invasion	114	96
Invasion	5	10
^dPre-operation PSA Level (ng/ml) (n= 225) **
Median (Range)	18.00 (21.69, 30.42)	26.47 (31.30, 42.63)	0.002
Mean	26.06	36.97	0.002
^bGleason Score (n = 225)*
Gleason≤6	42	22	0.016
Gleason≥7	77	84	0.016
^bBiochemical Recurrence (n = 225)**
Yes(≥0.2ng/ml)	45	77	<0.000
No(<0.2ng/ml)	74	29	<0.000

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