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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Overexpression of proteasomal activator PA28α serves as a prognostic factor in oral squamous cell carcinoma

Fig. 1

Expression of PA28α related to carcinogenesis and prognosis in OSCC tissues. a Oncomine analysis of PA28α mRNA abundance in human primary OSCCs compared with human normal oral tissue. b PA28α expression pattern in 158 oral carcinoma clinical samples. IHC staining showed the expression of PA28α increased paralleled with progression from normal epithelium to premalignant dysplasia to invasive carcinoma by using polyclonal antibody to PA28α. c PA28α expression correlates with OSCC prognosis in 98 clinical OSCC samples. IHC staining showed those cases with poorer prognosis exhibited stronger staining. a, a moderate-differentiated OSCC sample with disease free survival. b, a well-differentiated OSCC sample with regional neck recurrence within 2 years postoperation. c, a well-differentiated OSCC sample with cancer-related death with 4 years postoperation. The scale bar represent 100 μm

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