Fig. 4
PA28α knockdown in CAL27 and HSC3 suppresses cell invasion, migration and wound healing properties in vitro. a Matrigel invasion assay, PA28α knockdown in CAL27 and HSC3 inhibits cell invasion. b Transwell migration assay, PA28α knockdown in CAL27 and HSC3 inhibits cell migration. c Wound healing assay, scratch wound of PA28α knockdown in CAL27 and HSC3 cells were not completely closed in 48 h, whereas cells transfected with siRNA-Control the scratch wound were successfully closed in 48 h. Data are reported as means ± SEM for three independantly experiments. (ANOVA or T test,, * p < 0.05, ** p < 0.01, *** p < 0.001)